Product Description

Oxramet 5mg/500mg Tablet IR contains Dapagliflozin which belongs to the group of medicines called Antidiabetic agents. It is used to treat Type II diabetes mellitus in adults and in children (aged 10 years or older) when diet and exercise does not result in adequate control on blood glucose levels. It can also be used to treat heart failure and chronic kidney disease (reduced kidney function) in adults.

Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.

Oxramet 5mg/500mg Tablet IR is a combination of two medicines used to treat type 2 diabetes mellitus. It helps control the high blood sugar levels seen in diabetes. This reduces the chances of serious complications of diabetes and also helps prevent heart disease.

Oxramet 5mg/500mg Tablet IR can be taken with or without food at any time of day but you should try to take it at the same time every day. The dose will be decided by your doctor. Don’t stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor

During therapy with Oxramet 5mg/500mg Tablet IR, your doctor might regularly monitor your blood sugar levels and kidney functions to avoid the risk of unwanted side effects. He/she might also ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption to achieve better results. You must also check your feet regularly and follow the foot care advice given by your doctor as a precaution.

Before taking Oxramet 5mg/500mg Tablet IR inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have type I diabetes, severe low blood pressure, severe dehydration or conditions which can cause dehydration (such as nausea, vomiting, fever, serious illness any surgery etc.).

Oxramet 5mg/500mg Tablet IR is not recommended for use in pregnant or breastfeeding women. Therefore, consult your doctor for advice. The most common side effects of taking Oxramet 5mg/500mg Tablet IR are genital infections, back pain, passing more urine, constipation, dizziness and rash. Contact your physician if any of these side effect worsens.

Uses

Type 2 Diabetes Mellitus

Key Benefits

Oxramet 5mg/500mg Tablet IR belongs to the anti-diabetic drug category, indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons whose blood sugar levels are high and not controlled by diet and exercise alone. Oxramet XR 10mg/1000mg Tablet consists of “Dapagliflozin” a sodium-glucose cotransporter-2 (SGLT-2) inhibitor responsible for inhibiting SGLT-2 enzymes in the kidney. Thus, it prevents the reabsorption of glucose from the blood filtered through your kidney, thereby increasing the glucose excretion from your body when you urinate.

HOW Oxramet 5mg/500mg Tablet IR WORKS

Oxramet 5mg/500mg Tablet IR is a SGLT-2 inhibitor. It works by blocking the action of a protein called SGLT-2 in the kidneys. This action prevents the reabsorption of glucose and sodium ions in the kidneys. As a result, it excretes excess glucose from the body in the form urine leading to decrease in blood sugar levels. It also protects kidney function and prevents it from further damage. Additionally, it reduces the strain on the heart and helps it to pump blood more efficiently with less pressure

Side Effect

Polyuria
Nausea
Vomiting
Dyslipidemia
Genital fungal infection
Nasopharyngitis (inflammation of the throat and nasal passages)
Urinary tract infection

Safety Advice

PREGNANCY
Oxramet 5mg/500mg Tablet IR is not recommended for use in pregnant women especially during the second and third trimesters. Therefore, inform your doctor before taking Oxramet 5mg/500mg Tablet IR if you are pregnant, think you may be pregnant or planning to have a baby.

BREASTFEEDING
It is not known whether Oxramet 5mg/500mg Tablet IR can pass through breast milk or not. Therefore, it should be used in breastfeeding women only if considered necessary by the physician.

DRIVING AND USING MACHINES
Oxramet 5mg/500mg Tablet IR does not affect your ability to drive or operate any heavy tools or machines. However, if it is combined with other antidiabetic medicines, it may cause dizziness, shakiness, or vision changes. Therefore, do not drive or handle any heavy tools if your ability is affected by Oxramet XR 10mg/500mg Tablet

ALCOHOL
It is not known whether Oxramet 5mg/500mg Tablet IR can pass through breast milk or not. Therefore, it should be used in breastfeeding women only if considered necessary by the physician.

KIDNEY
Oxramet 5mg/500mg Tablet IR should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

LIVER

Oxramet 5mg/500mg Tablet IR should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

ALLERGY
Do not take Oxramet 5mg/500mg Tablet IR if you are allergic to dapagliflozin.

OTHERS

It is unsafe to consume alcohol with Oxramet 5mg/500mg Tablet IR

Oxramet 5mg/500mg Tablet IR may be unsafe to use during pregnancy.

Your ability to drive may be affected if your blood sugar is too low or too high.

Oxramet 5mg/500mg Tablet IR is probably unsafe to use in patients with kidney disease and should be avoided.

Oxramet 5mg/500mg Tablet IR should be used with caution in patients with liver disease.

Dosage

Take Oxramet 5mg/500mg Tablet IR with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.